Pilot Study of DCE-MRI, DW-MRI, and MRS in the Assessment of Head and Neck Cancer Response to Chemo-radiation
DCE-MRI, DW-MRI, MRS have the potential to measure early cellular changes that occur in
response to successful therapies, such as chemoradiation, and have been demonstrated to be
early predictors not only of therapeutic response, but also of overall survival for other
malignancies. Our long-term goal is to use these imaging techniques to develop non-invasive
functional imaging methodologies that would be better predictors of pathological response
than the current clinical standard.
Observational Model: Case-Only, Time Perspective: Prospective
Determination of early or a prior prognostic markers of head and neck cancers, as measured by DCE-MRI, DW-MRI, and MRS, that characterize the differences between clinical responders and non-responders.
James A. Tanyi, PhD
Oregon Health and Science University
United States: Institutional Review Board
|Oregon Health and Science University||Portland, Oregon 97201|