Know Cancer

or
forgot password

Transfusion of Autologous Umbilical Cord Blood to Reverse Hyperglycemia in Children With Type 1 Diabetes - A Pilot Study.


Phase 1
1 Year
N/A
Open (Enrolling)
Both
Type 1 Diabetes, Children

Thank you

Trial Information

Transfusion of Autologous Umbilical Cord Blood to Reverse Hyperglycemia in Children With Type 1 Diabetes - A Pilot Study.


Inclusion Criteria:



- Must have a diagnosis of T1D and have stored umbilical cord blood (10 patients
sought) at the cord bank Vita 34.

- TID diagnosis will be defined as having a clear history of polydipsia, polyphagia,
polyuria, and weight loss consistent with a clinical diagnosis, diagnosis will mot be
based solely upon the presence of autoantibodies.

- Cord blood meets all selection and testing criteria (see below).

- Normal screening values for CBC, Renal function and electrolytes (BMP).

- Willing to comply with intensive diabetes management

- Not younger than 1 year of age

Exclusion Criteria:

- Have complicating medical issues that would interfere with blood drawing or
monitoring.

- Require chronic use of steroids or other immunosuppressive agents for other
conditions.

- Cord Blood with viability < 50%.

- Positive infectious disease markers from mothers blood or cord at time of collection
(See below for details).

- Any evidence of illness on planned infusion date (i.e. fever >38.5 C, vomiting,
diarrhea, wheezing, or crackles).

Type of Study:

Interventional

Study Design:

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Authority:

Germany: Paul-Ehrlich-Institut

Study ID:

593

NCT ID:

NCT00989547

Start Date:

Completion Date:

Related Keywords:

  • Type 1 Diabetes
  • Children
  • Diabetes Mellitus
  • Diabetes Mellitus, Type 1

Name

Location