Transfusion of Autologous Umbilical Cord Blood to Reverse Hyperglycemia in Children With Type 1 Diabetes - A Pilot Study.
- Must have a diagnosis of T1D and have stored umbilical cord blood (10 patients
sought) at the cord bank Vita 34.
- TID diagnosis will be defined as having a clear history of polydipsia, polyphagia,
polyuria, and weight loss consistent with a clinical diagnosis, diagnosis will mot be
based solely upon the presence of autoantibodies.
- Cord blood meets all selection and testing criteria (see below).
- Normal screening values for CBC, Renal function and electrolytes (BMP).
- Willing to comply with intensive diabetes management
- Not younger than 1 year of age
- Have complicating medical issues that would interfere with blood drawing or
- Require chronic use of steroids or other immunosuppressive agents for other
- Cord Blood with viability < 50%.
- Positive infectious disease markers from mothers blood or cord at time of collection
(See below for details).
- Any evidence of illness on planned infusion date (i.e. fever >38.5 C, vomiting,
diarrhea, wheezing, or crackles).