Trial Information

Comparison of the Central Venous Pressures Measured From the Peripherally Inserted Antecubital Central Catheters and the Internal Jugular Vein Central Catheters in Liver Transplantation Recipients

According to the protocol of LT in our hospital, a PICC is concomitantly inserted with the
pulmonary artery catheter (PAC) and 9-Fr advanced venous access (AVA) catheter for the LT
recipient at anesthetic induction. PAC and AVA catheter are usually removed on the second
postoperative day, and instead the PICC is used for the postoperative infusion of
prostaglandin E1 which is very irritable to small peripheral vein. So we fortunately had
chance to measure the CVPs from both CICC and PICC simultaneously in the same patients.

Methods: We measured the CVPs from the CICC and the PICC simultaneously during each main
surgical period of adult liver transplantation (preanhepatic, anhepatic, reperfusion, and
neo-hepatic period). Data are presented as means ± standard deviation. Statistical analysis
was performed using simple linear regression analysis to observe whether changes in the
PICCP were paralleled by simultaneous changes in the CICCP. Bland-Altman analysis was used
to determine the degree of agreement between the two devices. Analysis of variance was
performed to study whether there were changes in the CVP agreement profiles in regard to the
different time periods of LT. Differences were regarded as being statistically significant
when p values were less than 0.05.

(This observational study has been completed already.)