Inclusion Criteria:

- Patients with the following diseases:

- Acute myeloid or lymphoblastic leukemia in first complete remission if poor
prognosis documented by failure to response after initial induction
chemotherapy, or cytogenetic, or molecular studies.

- Acute leukemia in greater/equal second remission, or partial remission after
chemotherapy.

- High grade non Hodgkin's or Hodgkin's lymphoma with marrow involvement
resistant/ relapsed after second line therapy including high dose chemotherapy
and autologous SCT.

- CML in advanced or blastic phase.

- Plasma cell leukemia.

- Age 18-60 years.

- Karnofsky performance status of 70

- Adequate cardiac and pulmonary function. Patients with decreased LVEF less than/equal
to 40% or DLCO less than/equal to 50% of predicted will require clearance from
cardiology or pulmonary services, respectively, prior to enrollment on this protocol.

- Serum creatinine less than/equal to 1.5 mg/dL or Creatinine Clearance greater
than/equal to 50 ml/min .

- Serum bilirubin 2.0 mg/dl, SGPT less than/equal to 3 times the upper limit of normal

Exclusion Criteria:

- Life expectancy is severely limited by concomitant illness.

- Evidence of chronic active hepatitis or cirrhosis

- HIV-positive

- Patient is pregnant

- Patient or guardian is not able to sign informed consent.