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Evaluation of Efficacy of Photodynamic Therapy in Basal Cell Carcinoma


Phase 1
18 Years
N/A
Not Enrolling
Both
Basal Cell Carcinoma

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Trial Information

Evaluation of Efficacy of Photodynamic Therapy in Basal Cell Carcinoma


Background and Aim: Basal cell carcinoma (BCC) is the most common skin cancer .Photodynamic
therapy _as a novel , non-invasive therapeutic approach _may be considered a valuable
strategy. This study was designed with the aim of the evaluation of efficacy of PDT in
treatment of BCC and factors that may affect response rate.

Materials and Methods: This was a clinical trial which was done on 28 BCCs. Patients were
treated with ALA-PDT monthly for 1-6 sessions and evaluated for clinical response,cosmetic
results and probable side effects.


Inclusion Criteria:



- Histologically proven BCCs

Exclusion Criteria:

- rodent ulcer

- morphea type

- ANA +

- history of photosensitivity or photodermatosis or ingestion of phototoxic drugs
during last month

- pregnancy

- breast feeding

- age< 18

- history of another therapeutic intervention for bcc during last 6 months

Type of Study:

Interventional

Study Design:

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Clinical Response to Photodynamic Therapy

Outcome Time Frame:

immediately after termination of treatment course (with an average of 5 month after initiation of PDT)

Safety Issue:

Yes

Principal Investigator

Zohreh Tehranchi-nia, assist.prof.

Investigator Role:

Principal Investigator

Investigator Affiliation:

Skin Research Center

Authority:

Iran: Ethics Committee

Study ID:

pdt bcc1

NCT ID:

NCT00985829

Start Date:

January 2008

Completion Date:

March 2009

Related Keywords:

  • Basal Cell Carcinoma
  • basal cell carcinoma
  • photodynamic therapy
  • photo chemotherapy
  • basal cell epithelioma
  • Carcinoma
  • Carcinoma, Basal Cell

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