Prospective Study of the Effects of Helicobacter Pylori Eradication on Renal Functions and Proteinuria in Patients With Membranous Nephropathy
Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. It is thought
to be mainly a primary or idiopathic form; however, it may also be secondary to many other
diseases (e.g., infections, drugs, neoplasms and autoimmune diseases). In this study, the
presence of Helicobacter Pylori antigen was investigated in renal tissue from needle biopsy
samples, and the prevalence of H. pylori infection and the effects of H. pylori eradication
on proteinuria level in patients with MN will be investigated.
Interventional
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Daily proteinuria levels after Helicobacter Pylori eradication treatment
6 months
Yes
Yasar Caliskan, MD
Principal Investigator
Division of Nephrology, Istanbul Faculty of Medicine, Istanbul University
Turkey: Ethics Committee
20061976
NCT00983034
March 2006
July 2009
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