The Treatment of T1N0 Invasive Breast Carcinoma by Local Excision and Interstitial Implant
- When participants undergo surgery to remove the tumor (lumpectomy), it will be followed
by the placement of small flexible tubes throughout the region surrounding the site of
operation. These tubes will remain in place for 7-9 days following the surgery.
- The first 2-3 days, the tubes will not contain radioactivity. This time is used to do
all the calculations necessary for treatment and to check the findings in the breast
tissue that was removed. After 2-3 days, the tubes will be filled with a radioactive
wire which will remain in place for the next 5 days. During this period of time,
participants will be required to remain within the hospital. At the end of these 5
days, the radioactive wires and tubes will be removed.
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
To determine if interstitial implant brachytherapy to radical radiation doses is feasible following wide local excision of T1N0 breast carcinoma
Alphonse Taghian, MD, PhD
Massachusetts General Hospital
United States: Institutional Review Board
|Massachusetts General Hospital||Boston, Massachusetts 02114-2617|