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Collaborative Project on Potential Serum Markers for Malignant Melanoma, Metastatic Breast, Advanced Lung Pancreatic Carcinoma and Colorectal Cancer


N/A
N/A
N/A
Open (Enrolling)
Both
Breast Cancer, Colorectal Cancer, Lung Cancer, Melanoma (Skin), Pancreatic Cancer

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Trial Information

Collaborative Project on Potential Serum Markers for Malignant Melanoma, Metastatic Breast, Advanced Lung Pancreatic Carcinoma and Colorectal Cancer


OBJECTIVES:

Primary

- To assess which potential peptide and protein markers produced by human melanoma, lung,
breast, pancreatic, and colorectal cell lines may be detectable in serum of patients
from these five disease groups.

Secondary

- To conduct further extensive investigation with respect to identification of the
protein/peptide involved, determination of specificity for each cancer, and development
of more sensitive assays to look for such markers in a wider population of patients,
including those undergoing therapy.

OUTLINE: This is a multicenter study.

Blood samples are collected before surgical intervention or treatment to assess peptide and
protein markers.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Diagnosis of 1 of the following advanced metastatic malignancies:

- Malignant melanoma

- Lung cancer

- Breast cancer

- Pancreatic carcinoma

- Colorectal cancer

- Advanced and/or metastatic disease

- Hormone receptor status not specified

PATIENT CHARACTERISTICS:

- Menopausal status not specified

PRIOR CONCURRENT THERAPY:

- Not specified

Type of Study:

Observational

Study Design:

Time Perspective: Prospective

Outcome Measure:

Detection of peptide and protein markers in serum

Outcome Time Frame:

Ongoing

Safety Issue:

No

Principal Investigator

Martin Clynes

Investigator Role:

Principal Investigator

Investigator Affiliation:

National Institute for Cellular Biotechnology at Dublin City University

Authority:

Ireland: Irish Medicines Board

Study ID:

CDR0000644159

NCT ID:

NCT00974610

Start Date:

August 2008

Completion Date:

Related Keywords:

  • Breast Cancer
  • Colorectal Cancer
  • Lung Cancer
  • Melanoma (Skin)
  • Pancreatic Cancer
  • stage IV melanoma
  • recurrent melanoma
  • stage IV non-small cell lung cancer
  • recurrent non-small cell lung cancer
  • extensive stage small cell lung cancer
  • recurrent small cell lung cancer
  • stage IV breast cancer
  • recurrent breast cancer
  • male breast cancer
  • stage III pancreatic cancer
  • stage IV pancreatic cancer
  • recurrent pancreatic cancer
  • stage IV colon cancer
  • recurrent colon cancer
  • stage IV rectal cancer
  • recurrent rectal cancer
  • Breast Neoplasms
  • Colorectal Neoplasms
  • Lung Neoplasms
  • Melanoma
  • Pancreatic Neoplasms

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