Identification of Genes Involved in the Pathogenesis of Gliomas by Transcriptome Analysis
18 Years
N/A
Both
Brain and Central Nervous System Tumors
Trial Information
Identification of Genes Involved in the Pathogenesis of Gliomas by Transcriptome Analysis
OBJECTIVES:
Primary
- To better understand the pathophysiology of gliomas and identify molecular markers that
may predict prognosis and progression or that could identify new therapeutic
approaches.
Secondary
- To compare gene expression profiles, in terms of response to treatment, and attempt to
isolate subgroups of patients with objective response to certain types of chemotherapy
or radiotherapy.
OUTLINE: This is a multicenter study.
Biological samples are collected from patients at time of surgery for diagnostic and/or
treatment purposes.
Inclusion Criteria
DISEASE CHARACTERISTICS:
- Histologically confirmed glioma of any grade or rare primary brain tumor
- Planning surgery to remove the tumor
PATIENT CHARACTERISTICS:
- No urgent situation
- No known or suspected active infection
- Must not be deprived of liberty or protected by law
- Not pregnant or nursing
PRIOR CONCURRENT THERAPY:
- No concurrent participation in other trials that require a period of exclusion
Type of Study:
Observational
Study Design:
N/A
Outcome Measure:
Pathophysiology of gliomas and identification of molecular markers that may predict prognosis and progression or that could identify new therapeutic approaches
Safety Issue:
No
Principal Investigator
Luc Bauchet, MD
Investigator Affiliation:
University Hospital, Montpellier
Authority:
Unspecified
Study ID:
CDR0000626732
NCT ID:
NCT00967200
Start Date:
November 2003
Completion Date:
Related Keywords:
- Brain and Central Nervous System Tumors
- adult anaplastic astrocytoma
- adult diffuse astrocytoma
- adult glioblastoma
- adult giant cell glioblastoma
- adult gliosarcoma
- adult pilocytic astrocytoma
- adult pineal gland astrocytoma
- adult subependymal giant cell astrocytoma
- adult brain stem glioma
- adult choroid plexus tumor
- adult craniopharyngioma
- adult ependymoblastoma
- adult medulloblastoma
- adult supratentorial primitive neuroectodermal tumor (PNET)
- adult anaplastic ependymoma
- adult ependymoma
- adult myxopapillary ependymoma
- adult subependymoma
- meningeal melanocytoma
- adult meningeal hemangiopericytoma
- adult grade I meningioma
- adult grade II meningioma
- adult anaplastic meningioma
- adult papillary meningioma
- adult anaplastic oligodendroglioma
- adult oligodendroglioma
- adult pineoblastoma
- adult pineocytoma
- adult mixed glioma
- recurrent adult brain tumor
- Brain Neoplasms
- Glioma
- Nervous System Neoplasms
- Central Nervous System Neoplasms
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