Inclusion Criteria

DISEASE CHARACTERISTICS:

- Histologically or cytologically confirmed epithelial adenocarcinoma of the ovary

- Stage IC-IV disease

- No known or clinical evidence of brain metastasis

PATIENT CHARACTERISTICS:

- ECOG performance status 0-2

- Hemoglobin must be ≥ 90 g/L

- ANC ≥ 2 x 10^9/L

- Platelet count ≥ 100 x10^9/L

- Serum creatinine ≤ 115 μmol/L

- Total bilirubin ≤ 25 μmol/L

- Not pregnant or nursing

- No other serious disease which could affect protocol compliance and results

- No other prior malignancy within the past 5 years except for curatively treated
carcinoma in situ of the cervix or squamous carcinoma of the skin

- No peripheral neuropathy ≥ CTCAE version 3.0 grade 2

- No known hypersensitivity to any of the study drugs or their excipients

- No drug addiction or alcoholism

- No disorder which leads to the condition that contraindicates the use of the
investigational drugs, or that may affect the patient's compliance with the study
requirements

PRIOR CONCURRENT THERAPY:

- No prior chemotherapy or radiotherapy for ovarian cancer