Non-Invasive Prediction of Microvascular Invasion (MVI) in Hepatocellular Carcinoma (HCC) by Assessment of Tumor Oxygenation by Blood Oxygen Level-Dependent Magnetic Resonance Imaging (BOLD MRI)
- Patients with known Hepatocellular Carcinoma;
- Scheduled to undergo liver resection or liver transplantation.
- Estimated GFR (eGFR < 30 mL/min;
- MRI contrast allergy;
- General contraindications to MRI such as pacemaker, etc.;
- Prior tumor treatment such as transarterial chemoembolization or the tumor or
radiofrequency ablation or chemoradiation;
- Age less than 18 years.
Type of Study:
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
To assess the ability of BOLD MRI to predict microvascular invasion in hepatocellular carcinoma via assessment of intratumoral oxygenation.
Outcome Time Frame:
Kartik Jhaveri, MD
University Health Network, Toronto
Canada: Health Canada
- Hepatocellular Carcinoma
- Carcinoma, Hepatocellular