Trial Information
Search for Genetic Factors Predictive of Response to Chemotherapy in Patients With or Who Has a Mammary Adenocarcinoma in Neo-adjuvant or Metastatic Setting
OBJECTIVES:
- Identify constitutional gene variants associated with a change in response.
OUTLINE: Blood samples are collected periodically for analysis of genetic factors.
Inclusion Criteria
DISEASE CHARACTERISTICS:
- Histologically confirmed breast carcinoma
- Received first-line chemotherapy (in neoadjuvant or metastatic setting) comprising
anthracyclines and/or taxanes, including for a second primary cancer
- Patient agrees to conservative surgery
- Hormone receptor status not specified
PATIENT CHARACTERISTICS:
- Menopausal status not specified
- No contraindication for chemotherapy comprising anthracyclines and/or taxanes
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
- No prior adjuvant therapy
Type of Study:
Observational
Study Design:
N/A
Outcome Measure:
Histologic complete response (Chevallier and Sataloff) or tumor response (RECIST)
Safety Issue:
No
Principal Investigator
Jacques Bonneterre, MD, PhD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Centre Oscar Lambret
Authority:
Unspecified
Study ID:
CDR0000633531
NCT ID:
NCT00959556
Start Date:
November 2007
Completion Date:
Related Keywords:
- Breast Cancer
- recurrent breast cancer
- stage IA breast cancer
- stage IB breast cancer
- stage II breast cancer
- stage IIIA breast cancer
- stage IIIB breast cancer
- stage IIIC breast cancer
- stage IV breast cancer
- Breast Neoplasms