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Application of Magnetic Resonance Fat-Free Imaging

18 Years
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Trial Information

Application of Magnetic Resonance Fat-Free Imaging

In addition, we will perform the same scans on 4 volunteers who have no history of sarcoma.
Scanning volunteers will allow us to optimize the imaging technique by 1.) Determine the
best combination of pulse-sequence and magnetization transfer technique to obtain the
greatest contrast and 2.) Determine the parameters of repetition time (TR), echo time (TE)
and magnetization transfer time and power in order to reduce overall image acquisition time
while optimizing image quality. Honing this technique on volunteers will allow us to
decrease scan time and potential discomfort for patients.

Inclusion Criteria:

- Participant is capable of providing verbal consent.

- 18 years of age or older.

- Participants will belong to one of the following two categories:

- Patient with a known or suspected soft tissue sarcoma of the extremity or trunk who
is/will be scheduled for an MRI scan as part of their routine care, -OR--

- Volunteer with no history of sarcoma.

Type of Study:


Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

To determine if our magnetization transfer fat-free imaging methods produce fat suppression images of sarcoma that are better, equal to or less in quality than fat-suppressed T2-weighted MRI images.

Outcome Time Frame:

2 years

Safety Issue:


Principal Investigator

Samuel Singer, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Memorial Sloan-Kettering Cancer Center


United States: Institutional Review Board

Study ID:




Start Date:

July 2009

Completion Date:

July 2013

Related Keywords:

  • Sarcoma
  • Sarcoma
  • soft tissue
  • MRI
  • Questionnaire
  • 09-078
  • Sarcoma



Memorial Sloan-Kettering CancerCenterNew York, New York  10065