Targeted Therapy With Lapatinib in Patients With Recurrent Pituitary Tumors Resistant to Standard Therapy
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome in nonfunctioning adenomas: stabilization of tumor volume and mean tumor diameter on MRI. Stabilization is defined as < 2 mm change in any dimension. MRIs will be performed at baseline and at 3 and 6 months.
baseline and every 3 months
Shlomo Melmed, MD
Cedars-Sinai Medical Center
United States: Institutional Review Board
|Pituitary Center Cedars-Sinai Medical Center||Los Angeles, California 90048|