Trial Information

A Prospective Quantification of Patient-Reported Adverse Events Following Trans-Rectal Ultrasound-Guided Intra-Prostatic Marker Insertion

Precise localisation of target organs has become increasingly important with the routine use
of steep dose gradients from conformal and intensity modulated radiotherapy. This is
particularly challenging when soft tissue target organs, such as the prostate, displace
relative to bony anatomy. Although novel imaging techniques are being developed for the
direct visualisation of such soft tissue structures, contrast and image quality is currently
limited. However, the use of radio-opaque intra-prostatic fiducial markers(IPM) during high
dose radiotherapy has proven very effective in terms of improving accuracy, and decreasing
toxicity.