Efficacy & Tolerability of Progesterone Vaginal Tablets (Endometrin®) in Menopausal Women Treated by Estrogen Replacement Therapy - Phase II Comparative Study
Estrogen Replacement Therapy must be opposed by progesterone in order to protect the
endometrium of uncontrolled proliferation and prevent endometrial cancer, in women with an
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Comparing the proportion of women with endometrial thickness not exceeding 8mm and change not exceeding 3mm between the two groups.
Boris Kaplan, prof
Rabin Medical Center Beilinson Hospital
Israel: Ministry of Health