Transbronchial Needle Aspiration in the Diagnosis of Peripheral Pulmonary Malignancy: Yield and Predictors of a Positive Aspirate
18 Years
76 Years
Both
Pulmonary Nodule, Pulmonary Mass
Trial Information
Transbronchial Needle Aspiration in the Diagnosis of Peripheral Pulmonary Malignancy: Yield and Predictors of a Positive Aspirate
In a recent systematic literature review (Rivera PM, Mehta AC; Chest 2007; 132: 1318-1488)
TBNA showed the highest sensitivity in the diagnostic bronchoscopic approach to peripheral
pulmonary lesions, as compared to the other available sampling techniques (transbronchial
biopsy, brushing, washings). However, the Authors conclude that the data regarding TBNA in
this setting deserve cautious interpretation because of the limited number of studies and
the large differences in sample size). We designed the present study to assess the
performance characteristics of TBNA, alone and in comparison with those of transbronchial
biopsy, in the diagnosis of peripheral pulmonary lesions.
Inclusion Criteria:
- Age 18 years and older
- Pulmonary nodule (< 3 cm) or mass (> 3 cm) at computed tomography
Exclusion Criteria:
- Refusal to sign informed consent
- Uncontrolled coagulopathy
- Pregnancy
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Outcome Measure:
Assess sensitivity, specificity and accuracy of TBNA in the diagnosis of peripheral pulmonary lesions
Outcome Time Frame:
1 year
Safety Issue:
No
Authority:
Italy: Ethics Committee
Study ID:
02-Trisolini
NCT ID:
NCT00917137
Start Date:
July 2008
Completion Date:
June 2010
Related Keywords:
- Pulmonary Nodule
- Pulmonary Mass
- Lung cancer
- Lung nodule
- Transbronchial needle aspiration
- Transbronchial lung biopsy
- Bronchoscopy
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