Can 3D Ultrasound Be Used Reproducibly by Radiation Therapists in Partial Breast Image-Guided Radiation Therapy?
TB Contouring The CT1, CT2, and US1 tumor beds will be manually contoured on the RM
workstation by one of the study radiation therapists. Contouring will be performed using
previously defined contouring guidelines. Available automatic contouring tools, including
the 'interpolate' contouring function, may be utilized and contouring times will be
IGRT Assessment The patient will be set up on the breast board in treatment position. The
'ultra path' component of the Clarity system, which displays the path of the previous US
acquired at CT simulation, will be used to guide the acquisition of US2. Although performed
in the simulator room, the Clarity system will be used in 'treatment mode' thus simulating
Clarity as it is used for IGRT. The study RT will first acquire the US2 scan. All steps
following the acquisition of US2 will be performed off-line on the RM workstation without
the need for further simulator or patient time.
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Will the Clarity of breast IGRT product have the potential to improve localization through its ability to compare 3DUS at the time of planning to 3DUS at the time of treatment.
Outcome will be measured three times during the 3DUS
British Columbia Cancer Agency
Canada: Ethics Review Committee