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Familial and Atypical Urothelial Cancer Registry


N/A
18 Years
N/A
Open (Enrolling)
Both
Urothelial Cancer, Renal Pelvis Cancer, Ureter Cancer, Bladder Cancer

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Trial Information

Familial and Atypical Urothelial Cancer Registry


Inclusion Criteria:



Urothelial Cancer Cases

- Must be ≥ 18 years of age AND

- Must have a diagnosis of urothelial cancer AND

- Must be an English-speaker

Non-Cancer Control Group

- Must be ≥ 18 years of age AND

- Must not have cancer or a personal history of cancer, with the exception of skin
cancer. AND

- Must not be a blood relative of cases AND

- Must not be a blood relative of another control AND

- Must be an English-speaker

Family Member Control Group:

In select kindreds with a high prevalence of bladder cancer and/or very early onset
bladder cancer, first- and second-degree family members of probands may be contacted by
the MSKCC study team and invited to complete the questionnaire and submit a saliva sample.

- Must be ≥ 18 years of age AND

- Must be a blood relative of a case participant AND

- Must be an English-speaker

Exclusion Criteria:

- Have any condition, which in the opinion of the primary MSKCC clinician or
investigators precludes their ability to provide informed consent.

Type of Study:

Observational

Study Design:

Observational Model: Case Control, Time Perspective: Prospective

Outcome Measure:

Determine whether single nucleotide polymorphisms in regions discovered from whole genome scans, such as 8q24 & chromosome 3, & candidate genes, include NAT2 & GSTM1, prev found to be assoc with bladder ca risk, are assoc with UC in this study population

Outcome Time Frame:

2 years

Safety Issue:

No

Principal Investigator

Dean Bajorin, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Memorial Sloan-Kettering Cancer Center

Authority:

United States: Institutional Review Board

Study ID:

09-025

NCT ID:

NCT00902590

Start Date:

May 2009

Completion Date:

May 2014

Related Keywords:

  • Urothelial Cancer
  • Renal Pelvis Cancer
  • Ureter Cancer
  • Bladder Cancer
  • renal pelvis
  • ureter
  • bladder
  • 09-025
  • Renal Pelvis, Ureter, Bladder Cancer
  • Urinary Bladder Neoplasms
  • Kidney Neoplasms
  • Ureteral Neoplasms
  • Pelvic Neoplasms

Name

Location

Memorial Sloan-Kettering Cancer CenterNew York, New York  10021
Memorial Sloan-Kettering Cancer Center at Mercy Medical CenterRockville Centre, New York  11570
Memorial Sloan-Kettering at Basking RidgeBasking Ridge, New Jersey  07920
Memorial Sloan-Kettering Cancer Center @ SuffolkCommack, New York  11725
Memoral Sloan Kettering Cancer Center@PhelpsSleepy Hollow, New York