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Advanced Tumor Bank Project

Open (Enrolling)
Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific

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Trial Information

Advanced Tumor Bank Project


- To provide a tissue and cell repository to be used by Wake Forest University
Comprehensive Cancer Center (WFUCCC) investigators.

- To provide specialized research pathology services to these investigators.

OUTLINE: Tumor and normal tissue in the resected specimen (when possible) are harvested and
collected from patients undergoing planned surgery or biopsy. Additionally, any normal
tissue and/or fluid removed in the course of the operation (e.g., cerebrospinal fluid during
brain tumor resection) may also be stored for use in analyzing changes from normal tissue to
cancerous tissue. Specimens are rapidly frozen in liquid nitrogen to preserve the mRNA,
proteins, lipids, and DNA in the samples for future analysis. Tissue is stored for research
projects on tumors and treatment of cancer patients. Research may involve analysis of the
genetic makeup of the tumor tissue. Genes may be cloned and living cells cultured from the
stored tissue. Blood is also collected during surgery. Samples are maintained and cataloged
for future retrieval.

Information about medical history is collected from patient medical records. This
information includes the following: medical diagnosis; specific information about treatment;
other medical conditions; medical data (i.e., laboratory test results, tumor measurements,
CT scans, MRI scans, x-rays, and pathology results); side effects experienced and treatment
for side effects; long-term information about general health status and the status of
disease; data that may be related to tissue and/or blood samples collected; and identifying
numbers or codes (i.e., social security number and medical record number).

Inclusion Criteria:

- Clinically suspected solid tumor AND scheduled for surgical resection and/or biopsy

Type of Study:


Study Design:

Observational Model: Case-Only

Outcome Measure:

Tissue and cell repository for Wake Forest University Comprehensive Cancer Center investigators

Outcome Time Frame:

Day 1

Safety Issue:


Principal Investigator

Edward A. Levine, MD

Investigator Role:

Study Chair

Investigator Affiliation:

Comprehensive Cancer Center of Wake Forest University


United States: Institutional Review Board

Study ID:




Start Date:

May 2004

Completion Date:

Related Keywords:

  • Unspecified Adult Solid Tumor, Protocol Specific
  • Unspecified Childhood Solid Tumor, Protocol Specific
  • unspecified adult solid tumor, protocol specific
  • unspecified childhood solid tumor, protocol specific
  • Neoplasms



Wake Forest University Comprehensive Cancer CenterWinston-Salem, North Carolina  27157-1096