VORTEX-BIOBANK: Prospective Sample Collection for the VORTEX Randomised Radiotherapy Trial in Patients With Extremity Soft Tissue Sarcoma [VORTEX BIOBANK]
- Determine early in the course of treatment which patients treated on clinical trial
CRUK-VORTEX have an increased likelihood of distant metastases so as to highlight
individuals who might benefit from early adjuvant systemic therapy.
OUTLINE: This is a multicenter study.
Tumour and normal tissue samples will be taken at the time of surgery during treatment on
clinical trial CRUK-VORTEXand preserved for future microarray analyses. Tissue microarrays
will be produced from both tumor and normal tissues. Blood samples will be collected for
future DNA analysis.
Increased likelihood of distant metastases
Christie Hospital NHS Foundation Trust