The CALGB Lung Cancer Tissue Bank
- Collect and store frozen specimens of tumor, involved lymph node (when available), and
grossly uninvolved adjacent lung tissues obtained from patients during surgical staging
or resection of lung cancer, for later molecular analysis.
- Collect and store frozen blood samples from these patients, as a source of reference
DNA to assess somatic mutations associated with tumor or preneoplastic "normal" lung
and to assess levels of circulating markers.
- Correlate these analyses with historical, clinical, pathological, and outcome
OUTLINE: Grossly viable tumor and grossly normal lung tissue are identified and removed from
patient surgical specimens and cryopreserved until shipment to the CALGB Lung Cancer Tissue
Bank for future use in research. Blood specimens are obtained pre- or intra-operatively and
shipped immediately to the Tissue Bank.
Patients do not receive the results of the research.
PROJECTED ACCRUAL: Samples from approximately 100 patients per year will be collected for at
least 5 years.
Collection and storage of frozen specimens of tumor, involved lymph node (when available), and grossly uninvolved adjacent lung tissues obtained from patients during surgical staging or resection of lung cancer
David J. Sugarbaker, MD
Dana-Farber/Brigham and Women's Cancer Center
|Roswell Park Cancer Institute||Buffalo, New York 14263|
|CCOP - Christiana Care Health Services||Wilmington, Delaware 19899|
|Ellis Fischel Cancer Center at University of Missouri - Columbia||Columbia, Missouri 65203|
|Veterans Affairs Medical Center - Asheville||Asheville, North Carolina 28805|
|Fletcher Allen Health Care - University Health Center Campus||Burlington, Vermont 05401|
|SUNY Upstate Medical University Hospital||Syracuse, New York 13210|
|Rhode Island Hospital Comprehensive Cancer Center||Providence, Rhode Island 02903|
|Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute||Boston, Massachusetts 02115|
|Masonic Cancer Center at University of Minnesota||Minneapolis, Minnesota 55455|
|Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis||St. Louis, Missouri 63110|
|Cancer Institute of New Jersey at Cooper - Voorhees||Voorhees, New Jersey 08043|
|Allegheny Cancer Center at Allegheny General Hospital||Pittsburgh, Pennsylvania 15212|
|Tunnell Cancer Center at Beebe Medical Center||Lewes, Delaware 19958|
|Union Hospital of Cecil County||Elkton MD, Maryland 21921|
|Dana-Farber/Brigham and Women's Cancer Center||Boston, Massachusetts 02115|
|Duke Cancer Institute||Durham, North Carolina 27710|
|Miriam Hospital||Providence, Rhode Island 02906|
|Alle-Kiski Medical Center||Natrona Heights, Pennsylvania 15065|
|Forbes Regional Hospital||Monroeville, Pennsylvania 15146|