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The CALGB Leukemia Tissue Bank

Open (Enrolling)
Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms

Thank you

Trial Information

The CALGB Leukemia Tissue Bank


- Collect and store specimens from newly diagnosed patients with acute or chronic
leukemia or myelodysplastic syndromes enrolled on a CALGB protocol.

OUTLINE: This is a multicenter study.

Bone marrow aspirate and blood specimens are obtained from patients at diagnosis, remission,
or relapse and stored. Buccal smears are obtained at diagnosis, and DNA is extracted and

PROJECTED ACCRUAL: Samples from approximately 1,500 patients will be collected for this
study within 5 years.

Inclusion Criteria


- One of the following diagnoses:

- Acute leukemia

- Chronic leukemia

- Myelodysplastic syndrome

- Newly diagnosed disease

- Enrolled on a CALGB treatment protocol

- Must enroll on this study before receiving any therapy for malignancy


- Not specified


- Not specified

Type of Study:


Study Design:


Outcome Measure:

Collection and storage of specimens from newly diagnosed patients with acute or chronic leukemia or myelodysplastic syndromes enrolled on a CALGB protocol

Safety Issue:


Principal Investigator

Michael A. Caligiuri, MD

Investigator Role:

Study Chair

Investigator Affiliation:

Ohio State University Comprehensive Cancer Center



Study ID:




Start Date:

May 1996

Completion Date:

Related Keywords:

  • Leukemia
  • Lymphoma
  • Myelodysplastic Syndromes
  • Myelodysplastic/Myeloproliferative Neoplasms
  • accelerated phase chronic myelogenous leukemia
  • acute lymphocytic leukemia
  • acute undifferentiated leukemia
  • blastic phase chronic myelogenous leukemia
  • chronic myelomonocytic leukemia
  • chronic phase chronic myelogenous leukemia
  • meningeal chronic myelogenous leukemia
  • progressive hairy cell leukemia, initial treatment
  • prolymphocytic leukemia
  • stage 0 chronic lymphocytic leukemia
  • stage I adult T-cell leukemia/lymphoma
  • stage I chronic lymphocytic leukemia
  • stage II adult T-cell leukemia/lymphoma
  • stage II chronic lymphocytic leukemia
  • stage III adult T-cell leukemia/lymphoma
  • stage III chronic lymphocytic leukemia
  • stage IV adult T-cell leukemia/lymphoma
  • stage IV chronic lymphocytic leukemia
  • untreated adult acute lymphoblastic leukemia
  • untreated adult acute myeloid leukemia
  • untreated childhood acute lymphoblastic leukemia
  • untreated childhood acute myeloid leukemia and other myeloid malignancies
  • untreated hairy cell leukemia
  • de novo myelodysplastic syndromes
  • myelodysplastic/myeloproliferative neoplasm, unclassifiable
  • secondary myelodysplastic syndromes
  • secondary acute myeloid leukemia
  • juvenile myelomonocytic leukemia
  • childhood myelodysplastic syndromes
  • Neoplasms
  • Leukemia
  • Lymphoma
  • Myelodysplastic Syndromes
  • Preleukemia
  • Myeloproliferative Disorders
  • Myelodysplastic-Myeloproliferative Diseases



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