Phase III Radiation Therapy vs Pelvic Node Resection for Previously Untreated Invasive Squamous Cell Carcinoma of the Vulva With Positive Groin Nodes
OBJECTIVES: I. Compare the efficacy of pelvic node resection vs. bilateral groin and pelvic
node irradiation for invasive squamous cell carcinoma of the vulva in patients having
positive groin nodes.
OUTLINE: Randomized study. Arm I: Surgery. Deep pelvic node dissection on sides containing
positive nodes only. Arm II: Radiotherapy. Megavoltage (1 MeV or greater) to bilateral groin
and pelvic nodes.
PROJECTED ACCRUAL: Anticipated annual accrual is approximately 200 patients, with an active
phase estimated at 2.5-3 years. Protocol closed July 1984.
Allocation: Randomized, Primary Purpose: Treatment
George C. Lewis, MD
Kimmel Cancer Center (KCC)
United States: Federal Government