Effect of Myoma Removal on Blood Pressure and Erythropoetin Level
22 Years
55 Years
Female
Myoma, Hypertension
Trial Information
Effect of Myoma Removal on Blood Pressure and Erythropoetin Level
Background:
Myoma is the most common gynecoid tumor and produces many vasoactive substances, which may
be a cause for secondary hypertension. Early reports suggested the association of myoma and
hypertension. We studied the effect of myoma removal on hypertension and erythropoietin
level to evaluate this hypothesis.
Patients & Methods:
In this single centered prospective cohort study, in twenty eight patients who were
candidates for myomectomy due to myoma, 24 hour holter monitoring of blood pressure and
serum erythropoietin were checked before and 6 weeks after hysterectomy.
Inclusion Criteria:
- candidate for myoma removal by hysterectomy
- operable
- hysterectomy is indicated
Exclusion Criteria:
- patient refusal
- inoperable patients
- other secondary cases of hypertension
Type of Study:
Interventional
Study Design:
Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Diagnostic
Outcome Measure:
24 hour holter monitoring of blood pressure
Outcome Time Frame:
6 weeks
Safety Issue:
No
Principal Investigator
javad kojuri, M.D.
Investigator Role:
Principal Investigator
Investigator Affiliation:
Shiraz University of Medical Sciences
Authority:
Iran: Ministry of Health
Study ID:
88-2505
NCT ID:
NCT00898170
Start Date:
May 2008
Completion Date:
March 2009
Related Keywords:
- Myoma
- Hypertension
- myoma
- hypertension
- erythropoetin
- blood pressure
- erythropoetin level
- Hypertension
- Myoma
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