Gene Expression Profiles in Primary and Metastatic Pancreatic Cancer
- Compare the gene expression profiles of pancreatic cancer cells from the primary and
metastatic sites in patients with metastatic pancreatic cancer.
- Characterize the function of the differentially upregulated and downregulated genes
identified by comparing the gene expression profiles of primary and metastatic cells in
OUTLINE: Fresh biopsy samples are collected for gene expression profiling and other
PROJECTED ACCRUAL: A total of 10 patients will be accrued for this study.
Observational Model: Case-Only, Time Perspective: Prospective
Gene expression profiles
at time of biopsy
Philip A. Philip, MD, PhD, FRCP
Barbara Ann Karmanos Cancer Institute
United States: Federal Government
|Barbara Ann Karmanos Cancer Institute||Detroit, Michigan 48201|