Evaluation of the Detection of Tumor Cells in Bone Marrow and Blood in Patients With Choroid Melanoma
OBJECTIVES:
Primary
- Develop and validate a method of detecting tumor cells in the bone marrow and blood in
patients with metastatic choroid melanoma.
OUTLINE: While patients are under general anesthesia for standard treatment of their
disease, samples of bone marrow from the iliac crest and blood are collected. Samples are
analyzed for the expression of tyrosinase and Melan-a via RT-PCR.
Observational
N/A
Detection of micro-metastatic cells in 20 x 10^6 nucleated cells
No
Pierre T. Dorval, MD
Principal Investigator
Institut Curie
United States: Federal Government
CDR0000633500
NCT00897624
November 2007
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