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Evaluation of the Detection of Tumor Cells in Bone Marrow and Blood in Patients With Choroid Melanoma


N/A
18 Years
N/A
Not Enrolling
Both
Intraocular Melanoma

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Trial Information

Evaluation of the Detection of Tumor Cells in Bone Marrow and Blood in Patients With Choroid Melanoma


OBJECTIVES:

Primary

- Develop and validate a method of detecting tumor cells in the bone marrow and blood in
patients with metastatic choroid melanoma.

OUTLINE: While patients are under general anesthesia for standard treatment of their
disease, samples of bone marrow from the iliac crest and blood are collected. Samples are
analyzed for the expression of tyrosinase and Melan-a via RT-PCR.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Choroid melanoma

- Metastatic disease

- Planning to undergo general anesthesia

PATIENT CHARACTERISTICS:

- Not pregnant or nursing

- No contraindications to the collection of a bone marrow sample

- No patient deprived of liberty or under trusteeship (including guardianship)

- No social or psychological situations that preclude the ability to give consent

PRIOR CONCURRENT THERAPY:

- Not specified

Type of Study:

Observational

Study Design:

N/A

Outcome Measure:

Detection of micro-metastatic cells in 20 x 10^6 nucleated cells

Safety Issue:

No

Principal Investigator

Pierre T. Dorval, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Institut Curie

Authority:

United States: Federal Government

Study ID:

CDR0000633500

NCT ID:

NCT00897624

Start Date:

November 2007

Completion Date:

Related Keywords:

  • Intraocular Melanoma
  • metastatic intraocular melanoma
  • ciliary body and choroid melanoma, medium/large size
  • ciliary body and choroid melanoma, small size
  • Melanoma
  • Uveal Neoplasms

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