Validation of a Serum Marker Panel for Early Detection of Breast Cancer in High-Risk Women
- Identify and validate serum biomarkers that can distinguish malignant from benign and
normal breast conditions in women at high risk or average risk for breast cancer.
- Standardize procedures for recruitment, characterization, and follow-up of participants
and collection, processing, storage, and analysis of specimens.
- Assess marker variability over time in healthy controls.
- Develop a shared specimen resource to support ongoing early detection research.
OUTLINE: Blood samples are collected every 6 months and assayed for the presence of
PROJECTED ACCRUAL: A total of 625 participants will be accrued for this study.
Time Perspective: Prospective
Biomarker evaluation for the early detection of breast cancer to improve outcomes for women at risk for breast cancer
Nicole Urban, ScD
Fred Hutchinson Cancer Research Center
United States: Federal Government