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Oral HPV Infection in Young Men


N/A
18 Years
21 Years
Not Enrolling
Male
Head and Neck Cancer, Infection, Precancerous Condition

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Trial Information

Oral HPV Infection in Young Men


OBJECTIVES:

- Estimate the prevalence of oral human papillomavirus (HPV) type 16, 18, 6, or 11
infection in young adult men.

- Assess the independent effect of distinct sexual practices, including kissing, oral
sex, and vaginal intercourse, on oral HPV prevalence.

- Estimate the 6-month incidence of HPV infection in this study population.

OUTLINE: Participants are assessed for oral human papillomavirus virus (HPV) infection
(i.e., types 16, 18, 6, and 11) and for known or potential risk factors associated with the
infection, including sexual behavior (e.g., kissing, performing oral sex, or vaginal
intercourse), demographic characteristics (e.g., age or race), and history of HPV or other
sexually transmitted infections. Prior exposure to HPV vaccine is also assessed.

Oral rinse samples are collected from participants at baseline and at 6 months for detection
of HPV genomic DNA in oral exfoliated cells. Baseline serum samples are also collected.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Currently enrolled at one of the following institutions:

- Johns Hopkins University

- University of Maryland

- Towson University

PATIENT CHARACTERISTICS:

- Able to understand the procedures and the potential risks involved as determined by
clinic staff

PRIOR CONCURRENT THERAPY:

- No prior GardasilĀ® off label

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Presence of an oral human papillomavirus (HPV) type 16, 18, 6 or 11 infection

Safety Issue:

No

Principal Investigator

Maura Gillison, MD, PhD

Investigator Role:

Study Chair

Investigator Affiliation:

Sidney Kimmel Comprehensive Cancer Center

Authority:

United States: Federal Government

Study ID:

JHOC-J0729, CDR0000554422

NCT ID:

NCT00897273

Start Date:

May 2007

Completion Date:

Related Keywords:

  • Head and Neck Cancer
  • Infection
  • Precancerous Condition
  • recurrent squamous cell carcinoma of the oropharynx
  • oropharyngeal cancer
  • oropharyngeal squamous cell carcinoma
  • infection
  • precancerous condition
  • human papilloma virus infection
  • Head and Neck Neoplasms
  • Precancerous Conditions
  • Oropharyngeal Neoplasms
  • Warts
  • Papillomavirus Infections

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