Inclusion Criteria:

- Have a lesion on mammogram, ultrasound or breast MRI that measured < 15 mm in
diameter, is considered suggestive or highly suggestive of malignancy according to
the Breast Imaging Reporting and Data System Atlas criteria (BIRADS 4b, 4c or 5), and
is scheduled for biopsy (needle biopsy and/or surgical biopsy).

OR

- Have a lesion on mammogram, ultrasound or breast MRI that measured > 15 mm in
diameter, is known to be malignant and is scheduled for surgery.

- Patient age > 18 years of age.

- Have a negative pregnancy test on the first day of the study, or must be
postmenopausal or surgically sterilized.

Exclusion Criteria:

- Patients will be excluded if they have a small lesion (< 15 mm) and have undergone
prior needle biopsy of the lesion (such biopsy may effectively remove all or part of
the lesion and angiogenesis associated with wound healing might confound imaging
results with 99mTc-NC100692).

- Patient's pregnancy is not negative on the first day of the study, or the patient is
unable to complete the pregnancy test

- Patient is unable to sit on a chair for 40 minutes