Pilot Randomized Study of Aerobic and Resistance Exercise for Women Undergoing Treatment for Breast Cancer With Taxanes.
This pilot study will test the effects of a tailored home-based walking (aerobic) and
strength training (resistance) exercise program for individuals receiving taxane-based
chemotherapy for breast cancer on neuropathy, breast cancer-related symptoms, cold thermal
sensation, vibratory sensation, gait & balance, upper and lower extremity muscle strength,
and quality of life.
The objective of this pilot study is to determine the effect size, feasibility and
acceptability of a 12-week combination exercise program consisting of aerobic exercise
(walking) and strength training for preventing or ameliorating the clinical manifestations
and symptoms of CIPN in individuals with Stage I-IIIa non-metastatic breast cancer.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Supportive Care
effect size for reduction of neuropathic symptoms
Baseline, 4, 8 12, 24 weeks
Constance Visovsky, PhD
University of Nebraska
United States: Institutional Review Board
|University of Nebraska Medical Center||Omaha, Nebraska 68198-3330|