Screening Protocol for Genetic Diseases of Allergic Inflammation and Mast Cell Homeostasis and Activation
This protocol is designed to screen subjects (and some family members) with suspected or
identified genetic diseases of allergic inflammation or mast cell homeostasis and
activation. Patients determined by clinical history and initial outside evaluation by their
referring physician to be of interest will be consented and enrolled into this study. Blood
specimens stored blood products and derivatives, and/or buccal swabs from such patients
and/or their family members will be obtained for research studies related to understanding
the genetic and biochemical bases of these diseases. Outside medical records may be
obtained for chart review to correlate clinical history to research laboratory testing
results. Results will be relayed to the referring physicians and, where applicable,
patients will be referred to other appropriate National Institutes of Health protocols for
additional clinical evaluation and treatment. The study will enroll up to 250 subjects and
family members over the next 5 years.
Designed to screen subjects with suspected or identified genetic diseases of mast cell homeostasis and activation. Blood specimens will be obtained for research studies related to understanding the genetic and biochemical bases of these diseases...
Kelly D Stone, M.D.
National Institute of Allergy and Infectious Diseases (NIAID)
United States: Federal Government
|National Institutes of Health Clinical Center, 9000 Rockville Pike||Bethesda, Maryland 20892|