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Coping With High Grade Glioma

18 Years
Not Enrolling
Brain Cancer

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Trial Information

Coping With High Grade Glioma

Inclusion Criteria:

- Caregivers will be defined as those individuals providing primary care for a patient
with pathology confirmed high grade glioma (WHO grades III or IV) attending their
treatment consultation at the Preston Robert Tisch Brian Tumor Center at Duke

- The caregiver may be a spouse/partner, family member or friend. Caregiver provides a
weekly minimum of 4 hours of caregiving

- caregiver is 18 years or older

- caregiver reading level at or above 8th grade

- caregiver sufficiently fluent in English

- the patient shows evidence of problems in depression, fatigue, sleep
disturbance, and/or cognitive impairment as per the treating neuro-oncologist
*the caregiver and patient are willing to be randomized to treatment or usual
care condition

- patient is within 3 months of initial diagnosis

- patient has life expectancy of at least 6 months or more

- the caregiver is willing to participate in treatment sessions using a telephone.

- If a patient dies during the active 12-week study phase, then the caregiver will be
transitioned to the follow-up phase or removed from the study and, if needed, be
referred for appropriate psychiatric or psychological treatment.

Exclusion Criteria:

- None

Type of Study:


Study Design:

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Outcome Measure:

Rate of adherence to coping skills training

Outcome Time Frame:

2 years

Safety Issue:


Principal Investigator

Bart Brigidi, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Duke University


United States: Institutional Review Board

Study ID:




Start Date:

December 2008

Completion Date:

October 2009

Related Keywords:

  • Brain Cancer
  • Brain Cancer
  • Coping
  • Glioma
  • National Brain Tumor Foundation
  • Duke
  • Brain Neoplasms
  • Glioma



Duke University Durham, North Carolina  27710