Motion Correction of Positron Emission Tomography (PET) Data Using Amplitude Gating
Routine PET/CT scans are taken while patients are breathing normally. The motions made by
breathing can reduce the image quality of the scan. Minimizing the effects of this motion
by taking the images and processing the scans differently may improve the image quality.
The PET/CT Scan:
If you agree to take part in this study, an elastic belt will be placed around your lower
chest/upper abdomen before your routine PET/CT scan. This belt is used to track your
breathing motion. This information will be used to help process the scan.
Your PET/CT scan will be performed as usual. During the scan, researchers will focus on
your lower chest/upper abdomen (areas that experience breathing motion). Having to focus on
this area might extend the scan by up to 10 minutes.
The additional scan time will not increase your radiation exposure since only PET scanning
will be performed.
Length of Study:
Your participation on this study will be complete when your scheduled PET/CT scan is
This is an investigational study. The imaging focused on your lower chest/upper abdomen
during the scan is investigational.
Up to 26 patients will take part in this study. All will be enrolled at M. D. Anderson.
Observational Model: Case-Only, Time Perspective: Prospective
Mean Difference Between Gated + Ungated PET/CT Scans
Scheduled PET/CT scans extended by 10 minutes
Osama R Mawlawi, PHD
UT MD Anderson Cancer Center
United States: Institutional Review Board
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