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Colorectal Cancer (CRC) Screening in First-Degree Relatives (FDRs) of Hispanic CRC Patients


N/A
18 Years
70 Years
Not Enrolling
Both
Colorectal Cancer

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Trial Information

Colorectal Cancer (CRC) Screening in First-Degree Relatives (FDRs) of Hispanic CRC Patients


CRC PATIENTS AND THEIR FDRS:

You will be asked to complete a questionnaire by telephone interview. The study researcher
who calls you will ask for your permission to audiotape the interview. The questionnaire
asks about your awareness of screening tests for colorectal cancer, your family's past use
of these screening tests, your attitudes toward colorectal cancer screening, and how you
discuss colorectal cancer risk and screening with your family and health care providers.
Some demographic information also will be collected (such as your age or marital status).
The questionnaire will take between 30 and 45 minutes to complete.

Your answers to the questions and your personal information will be kept strictly
confidential. Your questionnaire answers will be identified with a code number, rather than
a name, so that you cannot be identified. Audiotaped recordings will be destroyed after all
the data have been collected and studied (no longer than 5 years).

This is an investigational study. Up to 60 colorectal cancer patients and their close
relatives may be enrolled in the study. All will be enrolled at M. D. Anderson.

KEY INFORMANT:

You will be asked to complete a psychosocial interview either in person or by telephone.
The study staff member interviewing you will ask you for permission to audiotape the
interview. You will be asked to review the interview guides for colorectal cancer patients
and their first degree relatives (FDRs), and provide feedback about them. The interviewer
will ask for your opinions about Hispanics' awareness and understanding of colorectal cancer
screening. You will also be asked for your opinion about cultural beliefs and practices
that may influence participation in colorectal cancer screening. The interview will take
between 30 and 45 minutes to complete.

Your answers to the questions and your personal information will be kept strictly
confidential. Your questionnaire answers will be identified with a code number, rather than
a name, so that you cannot be identified. Audiotaped recordings will be destroyed after all
the data have been collected and studied (no longer than 5 years).

This is an investigational study. Up to 15 key informants may be enrolled in this study.
All will be enrolled at M. D. Anderson.


Inclusion Criteria:



1. Key Informants: Persons will be identified as potentially eligible key informants if
they are: 1) members of the Houston Hispanic Health Coalition, or if they are
identified through the Houston Hispanic Health Coalition as having professional
expertise relevant to this study. 2) Able to speak English or Spanish. 3) Able to
provide informed consent.

2. CRC Patients: Eligibility criteria include: 1) Living MDACC patients with a personal
history of colorectal adenocarcinoma (diagnosed as local or regional disease), who
are between the ages of 18 and 60 years, who are identified as Hispanic/Latino, and
who have living first degree relatives (siblings or children) between the ages of 40
and 70. 2) Able to provide informed consent. Eligible persons may speak either
English or Spanish.

3. First-degree relatives (FDRs): Eligibility criteria include: 1) First-degree
relatives (siblings and children) of the MDACC CRC cancer patients who are recruited
to this study, who are 40 to 70 years of age. 2) Able to provide informed consent.
Eligible persons may speak either English or Spanish.

4. Note: As described in the above inclusion criteria, this protocol involves recruiting
and interviewing of key informants, CRC patients, and eligible first-degree relatives
(FDRs) of CRC patients for three phases of the study.

Exclusion Criteria:

1. CRC Patients: CRC patients will be excluded if they have a history of a known
hereditary CRC syndrome (e.g., HNPCC, familial polyposis) or inflammatory bowel
disease (e.g., ulcerative colitis or Crohn's disease), or were diagnosed with distant
metastases.

2. First degree relatives: FDRs of eligible CRC patients will be excluded if they have a
history of a known hereditary CRC syndrome (e.g., HNPCC, familial polyposis) or
inflammatory bowel disease (e.g., ulcerative colitis or Crohn's disease), or have a
personal history of cancer (except non-melanoma skin cancer) or polyps.

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Outcome Measure:

To look at the knowledge, beliefs, and attitudes toward screening for colorectal cancer among Hispanic colorectal cancer patients and their close relatives.

Outcome Time Frame:

5 Years

Safety Issue:

No

Principal Investigator

Susan Peterson, PhD, MPH

Investigator Role:

Principal Investigator

Investigator Affiliation:

UT MD Anderson Cancer Center

Authority:

United States: Institutional Review Board

Study ID:

2004-0039

NCT ID:

NCT00838318

Start Date:

February 2004

Completion Date:

March 2010

Related Keywords:

  • Colorectal Cancer
  • Colorectal CancerScreening
  • CRC
  • Hispanic
  • CRC Patients
  • First-Degree Relatives
  • FDRs
  • Interviews
  • Colorectal cancer screening
  • CRCS
  • Key Informants
  • Colorectal Neoplasms

Name

Location
UT MD Anderson Cancer Center Houston, Texas  77030