Investigation of the Role of Functional Imaging in Characterising Radiotherapy Target Volumes and Assessing Disease Response in Patients Undergoing Chemoradiation for Head and Neck Cancer (HNC)
18 Years
N/A
Both
Head and Neck Cancer
Trial Information
Investigation of the Role of Functional Imaging in Characterising Radiotherapy Target Volumes and Assessing Disease Response in Patients Undergoing Chemoradiation for Head and Neck Cancer (HNC)
Adult patients who have a head and neck cancer and are planned to receive chemotherapy and
radiotherapy will be invited to participate in the study. Patients who are not in very good
health, have diabetes or kidney failure will not be considered for the study. Also patients
who can not undergo MRI scan or are allergic to contrast injection given prior to the scan
or have had any other form of cancer (except skin cancer) will also be excluded from the
study.
Inclusion Criteria:
- patients with histologically proven head and neck cancer, planed for chemotherapy and
radiotherapy
- age more than 18 years
- patient willing to participate and has signed a consent form
- patients in good physical status (WHO performance status 0-2)
Exclusion Criteria:
- patients in poor health (WHO performance status >2)
- patients with any other cancer apart from skin cancer
- patients with contraindications to MRI scan and IV contrast
- diabetic patients
- patients with renal failure
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Outcome Measure:
the number of patients completing the study protocol and adding to the library of images to be used for evaluation of new radiotherapy strategies and planning techniques including IMRT
Authority:
United Kingdom: Research Ethics Committee
Study ID:
CCR3123
NCT ID:
NCT00837980
Start Date:
February 2009
Completion Date:
November 2010
Related Keywords:
- Head and Neck Cancer
- head and neck cancer
- DW MRI
- PET
- DCE MRI
- functional imaging
- IMRT
- Head and Neck Neoplasms
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