Comparison of Skin Carotenoid Levels Between Subjects With History of Cutaneous Squamous Cell Carcinoma and Subjects With History of Basal Cell Carcinoma Versus a Control Group
There has been experimental and clinical research evaluating association of different
carotenoids and incidence of malignancies, including Non- Melanoma Skin Cancer (NMSC). An
easy and inexpensive way to determine which subjects would benefit from supplementation with
carotenoids or retinoids could be the measurement of skin carotenoid levels.The least
invasive way to perform it is through Raman spectroscopy which is a technique that uses a
laser light that can be used to quantify carotenoids on the skin. We will compare the skin
carotenoid levels of subjects with previous history of SCC or BCC and subjects without
history of previous NMSC.
Observational Model: Case Control, Time Perspective: Cross-Sectional
Skin Carotenoid Levels in Subjects With History of Squamous Cell Carcinoma Versus Control Subjects
Mean carotenoid levels in subjects with a history of squamous cell carcinoma were compared to mean carotenoid levels in control subjects without a history of nonmelanoma skin cancer.
Alexandra B Kimball, MD, MPH
Massachusetts General Hospital
United States: Institutional Review Board
|Clinical Unit for Research Trials in Skin - MGH||Boston, Massachusetts 02114|