RELATIONSHIP OF POLYMORPHISMS AND MUTATIONS OF EPIDERMAL GROWTH FACTOR RECEPTOR AND TYROSINE KINASE INHIBITORS RESPONSIVENESS IN NON-SMALL-CELL LUNG CANCER PATIENT
DNA will be isolated from blood samples or paraffin-embedded tumor specimens and than a
mutation analysis and SNPs genotyping will be done.
Observational Model: Cohort, Time Perspective: Retrospective
to evaluate the presence of EGFR- and AKT-DNA polymorphisms.
At the end of enrollment
Armando Santoro, MD
Istituto Clinico Humanitas
Italy: Ministry of Health