The Effect of Treatment on Circulating Tumor Cells in Bladder Cancer Patients With Muscle-invasive or Advanced Disease
The measurement of circulating tumor cells is pursued in several cancers including breast
and prostate cancer. The number of cells measured in these cancers has been shown to be
prognostic. There is little information on the presence or importance of circulating tumor
cells in bladder cancer. This trial is designed to determine if patients with advanced
bladder cancer have circulating tumor cells and if these circulating cells are affected by
treatment of the cancer.
Observational Model: Cohort, Time Perspective: Prospective
Effect of therapy
To determine the effect of therapy (cystectomy or chemotherapy) on circulating tumor cell (CTC) levels in bladder cancer patients.
baseline and then every 2 months
Thomas W. Flaig, MD
University of Colorado, Denver
United States: Institutional Review Board
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