Trial Information

Randomized Trial Comparing Endoscopy and Surgery for Pancreatic Cyst-gastrostomy

The purpose of this study is to examine endoscopic ultrasound guided celiac plexus
neurolysis (CPN) with analgesic therapy in patients with unresectable pancreatic cancer will
decrease the severity of abdominal pain when compared to analgesic therapy alone. The
specific primary aim of this study is to evaluate the efficacy of EUS-CPN + analgesic
therapy (Group 1) in pain relief of patients with unresectable pancreatic cancer when
compared with analgesic therapy (Group 2). The hypothesis will be tested by comparing the
changes in reported pain severity between those who receive EUS-CPN in addition to analgesic
therapy as compared to analgesic therapy alone.