A Randomized Controlled Trial of Treatment of Portal Vein Tumor Thrombus After Hepatocellular Carcinoma Resection
Hepatectomy is still the treatment of choice for hepatocellular carcinoma, but the prognosis
is not agreeable. Part of the patients may present portal vein tumor thrombus (PVTT) after
resection. PVTT might further increase the pressure of portal vein and lead to upper
gastrointestinal bleeding and worsening of hypersplenism which will endanger the life of the
patients. PVTT also plays the centre role of recurrence and metastasis of HCC. There is no
standard treatment available now for PVTT yet. TACE is mostly often used to treat the PVTT.
We aim to compare the effects of TACE and TACE plus laser ablation for treating patients
with PVTT.
Interventional
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
overall survival
2010
No
shen feng, M.D
Study Chair
Eastern Hepatobiliary Surgery Hospital Affiliated to Second Military Medical University
China: Ministry of Health
EHBH-RCT-2008-015
NCT00825669
December 2008
December 2010
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