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18 Months
70 Years
Not Enrolling
Breast Cancer

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Trial Information

It is known, that patients undergoing major surgery have problems maintaining upright
posture after major surgery. This can be due to fall in bloodpressure, with symptoms like
dizziness, nausea/vomiting and fainting.

With this investigation, we want to prove that anaesthesia is not the decisive factor, in
patients ability to maintain upright posture after surgery.

Inclusion Criteria:

- Patients having performed elective breast surgery

- Age between 18 and 70 years

- Patients who have given written consent to participate in the project after haven
completely understood the contents and limitations of the protocol

Exclusion Criteria:

- Patients who do not understand or speak Danish

- Patients who have not signed the informed consent or the written authority
pre-medication, except 1g paracetamol

- ASA > II

- Pregnant or breastfeeding

- Known to have Renal disease

- Known to have Psychiatric disorder (not considering the use of SSRI antidepressive)

- Need for crash induction or prone position

- Oesophageal varicoses

- Necrosis or cancer in: Mouth, Pharynx, Larynx or Oesophagus

- Coarctation or aneurism in the proximal Aorta

- Severe bleeding disease

Type of Study:


Study Design:

Time Perspective: Prospective

Outcome Measure:

To investigate orthostatic function, measured by Finapress

Principal Investigator

Henrik Kehlet, MD, Ph.D

Investigator Role:

Study Director

Investigator Affiliation:

dept of surgical patophysiology


Denmark: National Board of Health

Study ID:

OT after mastectomy



Start Date:

January 2009

Completion Date:

Related Keywords:

  • Breast Cancer
  • Mammae cancer patients
  • Breast Neoplasms