Development of a Predictive Model for Treatment Outcome and Treatment-related Morbidity in a Prospective Cohort Study of Patients With Lymphoma
Although the cure rate of lymphoma has been increased due to the development of newer
effective drugs, a substantial portion of patients is still suffered from relapse.
Furthermore, the treatment-related morbidity is another factor which can make the treatment
outcome worse in patients with lymphoma, especially elderly patients. Thus, this study is
going to assess following factors which amy probably affect the treatment outcome and the
risk of treatment-related morbidity.
1. Biologic factors associated with the aggressiveness of lymphoma
- molecular markers in serum, cytogenetic markers
2. Factors associated with the risk of treatment-related morbidity
- comorbidity, nutrition status, performance status, quality of life at diagnosis
Intervention Model: Single Group Assignment, Masking: Open Label
all cause mortality
Seok Jin Kim, MD, PhD
Samsung Medical Center
Korea: Food and Drug Administration