Phse II Study of Induction Chemotherapy With TPF Regimen Followed by Concurrent Chemoradiotherapy for Locally Advanced Nasopharyngeal Carcinoma
Concurrent chemoradiation is the standard treatment for locally advanced NPC. The survival
benefit gained from adding induction chemotherapy to concurrent chemoradiation has not been
defined yet. In the present clinical study, we hope to assess the tolerance and survival
benefits of induction chemotherapy followed by concurrent chemoradiation in patients with
stage III, IVa and IVb NPC.
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
3 and 5 years
XiaoShen WANG, M.D.
Department of Radiation Oncology, Cancer Hospital, Fudan University
China: Ethics Committee