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Drug /Cue Interactions In Alcohol-Tobacco Comorbidity


N/A
21 Years
55 Years
Open (Enrolling)
Both
Nicotine Dependence

Thank you

Trial Information

Drug /Cue Interactions In Alcohol-Tobacco Comorbidity


The present project will improve and expand upon previously published work in several ways.
First, Study 1 will assess reactivity to alcohol and smoking cues in the same session.
Second, both studies will include within-subjects design factors to manipulate alcohol and
nicotine intake, as well as cue types. Third, craving indices will represent three important
response domains: subjective, physiological, and behavioral (e.g., Niaura et al., 1991).
Fourth, each study will evaluate a range of drinkers and smokers, which will provide maximal
information concerning influences on alcohol and smoking cue reactivity across various
subject populations. The proposed studies are not only important from a theory development
perspective, but they will provide an excellent foundation for future laboratory-based and
clinical research.


Inclusion Criteria:



- English speaking persons who exhibit a range of alcohol consumption and smoking
patterns.

- Signed written consent form.

Exclusion Criteria:

- Females who are pregnant, nursing, or not using effective methods of birth control
will be excluded from participating.

Type of Study:

Interventional

Study Design:

Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention

Outcome Measure:

Psychophysiological Reactivity Assessment

Outcome Description:

To assess cravings and psychophysiological reactivity elicited by alcohol, smoking, and neutral cues following acute intake of alcohol and nicotine among individuals across a broad range of alcohol and cigarette use patterns (Study 1).

Outcome Time Frame:

approximately 5 weeks per participant

Safety Issue:

No

Principal Investigator

David Drobes, Ph.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

H. Lee Moffitt Cancer Center and Research Institute

Authority:

United States: Institutional Review Board

Study ID:

MCC-14671

NCT ID:

NCT00816231

Start Date:

May 2006

Completion Date:

December 2013

Related Keywords:

  • Nicotine Dependence
  • Prevention Intervention
  • Alcohol
  • Tobacco
  • Nicotine
  • Craving
  • Cue Reactivity
  • Cross Cue Reactions
  • Tobacco Use Disorder

Name

Location
H. Lee Moffitt Cancer Center & Research Institute Tampa, Florida  33612