Safety, Compatibility and Imaging Quality of ExAblate Prostate Applicator for Prostate Cancer
- Age of patients: up to 75 years.
- Men scheduled for radical prostatectomy due to prostate cancer.
- Patients who are able and willing to give consent and able to attend all study
- Contraindications to MRI including: claustrophobia, weight over 120 kg, implanted
ferromagnetic materials or foreign objects, and known intolerance to the MRI contrast
agent (e.g. Gadolinium or Magnevist)
- Severely abnormal coagulation (INR>1.5)
- Patients with unstable cardiac status including: unstable angina pectoris on
medication, patients with documented myocardial infarction within six months of
protocol entry, congestive heart failure requiring medication (other than diuretic),
patients on anti-arrhythmic drugs, severe hypertension (diastolic BP > 100 on
medication), and patients with cardiac pacemakers
- Severe cerebrovascular disease (multiple CVA or CVA within 6 months)
- Individuals who are not able or willing to tolerate the required prolonged stationary
supine position during imaging (approximately 1 hrs.)
- Any rectal pathology preventing probe insertion, (as active proctitis, ulcerative
colitis, fissure ani, diverticulitis, previous rectal surgery, IBD, etc…)
- Any spinal pathology that prohibits maintaining supine position for more then an hour
- Any previous radiation to the pelvis.