Effect of Preoperative Biliary Drainage on Postoperative Complications in Resectable Patients With Hilar Cholangiocarcinoma(Klatskin Tumor)
Preoperative biliary drainage(PBD) or not, is a Hot Spot issue in the management of Hilar
cholangiocarcinoma. Surgeons from Japan tend to perform PTBD(Percutaneous Transhepatic
Biliary Drainage) before a definite operation until the total bilirubin(TB) lower than
85μmol/L. For some patients needed to perform extended curative resection, PVE(Portal Vein
Embolization) is performed and thus the duration of PBD may be around six weeks and the
final TB is lower than 34μmol/L. Some tend to perform a definite curative operation in a
short time after diagnosis. There is no RCT research on the effect of PBD for the resectable
Hilar Cholangiocarcinoma patients to date.
Interventional
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
Incidence of postoperative complication
30 days after operation
Yes
Lijian Liang
Study Chair
Department of hepatobiliary, the first affiliated hospital, Sun Yat-sen University
China: Ministry of Health
SUMS-5010
NCT00797121
May 2008
May 2013
Name | Location |
---|