Does Endometrial Injury in the Non-Transfer Cycle Improve the IVF-ET Outcome in the Subsequent Cycle in Patients With Previous Failed IVF Cycles: A Randomized Control Trial
Study Design and Subjects: This is a randomized control study designed to evaluate the
effect of local injury to the endometrium in non-transfer cycle in patients with previous
Patients will be randomly allotted to control and intervention group The patients in the
intervention group Pipelle endometrial sampling 7-10th day and 24-26th day in the cycle
prior to IVF transfer cycle.
Outcome Measures: Clinical pregnancy rate,implantation rate and ongoing pregnancy rate.
SAMPLE SIZE: 100 PATIENTS (50 in each group).
Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
PRIMARY OUTCOME MEASURE:IMPLANTATION RATE;
SACHIN A NARVEKAR, MD
Bangalore Assisted Conception Centre
India: Institutional Review Board
endometrial injury study