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Pre-Operative Gleason Score and PSA and Clinical Stage in Predicting the Risk of Failure in Patients Undergoing Radiation Therapy for Localized Prostate Cancer


N/A
N/A
N/A
Open (Enrolling)
Male
Prostate Cancer, Radiation Toxicity

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Trial Information

Pre-Operative Gleason Score and PSA and Clinical Stage in Predicting the Risk of Failure in Patients Undergoing Radiation Therapy for Localized Prostate Cancer


OBJECTIVES:

- Evaluate the value of the pre-operative Gleason score, prostate-specific antigen level,
and clinical stage in predicting the risk of failure and death in patients who have
undergone radiotherapy for localized prostate cancer.

OUTLINE: This is a multicenter study.

Patient medical records are reviewed to collect data about pre-treatment prostate biopsy,
assigned Gleason score, prostate-specific antigen level, and radionucleotide bone scan.

Patients complete a Bowel Toxicity questionnaire to assess quality of life related to acute
and long-term bowel toxicity after radiotherapy.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Diagnosis of localized adenocarcinoma of the prostate

- Has undergone radiotherapy (external beam radiotherapy and/or brachytherapy) with or
without hormonal therapy for adenocarcinoma of the prostate in the UCSF Radiation
Oncology Department at San Francisco General Hospital or Veterans Administration
Medical Center of San Francisco between 1987 and 2006

PATIENT CHARACTERISTICS:

- Not specified

PRIOR CONCURRENT THERAPY:

- See Disease Characteristics

Type of Study:

Observational

Study Design:

N/A

Outcome Measure:

Value of the pre-operative Gleason score, prostate-specific antigen level, and clinical stage in predicting the risk of failure and death

Safety Issue:

No

Principal Investigator

Mack Roach, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

University of California, San Francisco

Authority:

Unspecified

Study ID:

CDR0000597000

NCT ID:

NCT00769223

Start Date:

February 1993

Completion Date:

Related Keywords:

  • Prostate Cancer
  • Radiation Toxicity
  • radiation toxicity
  • recurrent prostate cancer
  • stage IIB prostate cancer
  • stage IIA prostate cancer
  • stage III prostate cancer
  • stage I prostate cancer
  • stage IV prostate cancer
  • adenocarcinoma of the prostate
  • Prostatic Neoplasms
  • Radiation Injuries

Name

Location
UCSF Helen Diller Family Comprehensive Cancer Center San Francisco, California  94115