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Viral and Host Factors Associated With Development of Hepatitis B Virus-related Hepatocellular Carcinoma


N/A
18 Years
N/A
Open (Enrolling)
Male
Liver Cancer, Hepatitis B, Hepatitis C, Hepatobiliary Cancers Liver, Hepatobiliary Cancers

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Trial Information

Viral and Host Factors Associated With Development of Hepatitis B Virus-related Hepatocellular Carcinoma


Inclusion Criteria:

1. Patients diagnosed with liver cancer based on biopsy or serum AFP
level, associated with characteristic hypervascular liver tumors on triphasic spiral CT
scan or MRI.

2. Patients with non-cancer liver conditions such as cirrhosis, adenoma, cholangioma, or
nodular hyperplasia.

3. Patients with hepatitis B or hepatitis C viral infections not associated with liver
cancer.

Exclusion Criteria:No other patients except those listed above will be recruited.
Additionally, patients will be excluded if, upon looking through their medical records,
information required for data analysis are missing.

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

identify mutations in the hepatitis B virus genome that predisposes these high risk individuals to the development of liver cancer

Outcome Description:

We will be using blood specimens collected through another protocol

Outcome Time Frame:

one time

Safety Issue:

No

Principal Investigator

Samuel So

Investigator Role:

Principal Investigator

Investigator Affiliation:

Stanford University

Authority:

United States: Institutional Review Board

Study ID:

HEP0013

NCT ID:

NCT00767936

Start Date:

March 2008

Completion Date:

December 2014

Related Keywords:

  • Liver Cancer
  • Hepatitis B
  • Hepatitis C
  • Hepatobiliary Cancers Liver
  • Hepatobiliary Cancers
  • Carcinoma
  • Hepatitis
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Liver Neoplasms
  • Carcinoma, Hepatocellular

Name

Location
Stanford University School of Medicine Stanford, California  94305-5317